Paraoxonase

A key chemical in Porphyria
Copyright (C) 1995-2003, JVV




Porphyria
P-450
Paraox.



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Paraoxonase, a member of the A-oxonzse family, breaks down acetylcholinesterase inhibitors before they bind to the cholinestarases, thus protecting people from harm by low dose organophosphate pesticides exposure. Yet it is estimated that worldwide, 220,000 people are killed each year from such exposures.

Not all people have the same levels of these oxonases. Those who's bodies produce less of this are at higher risk in environments where pesticides are used.

See also Cytochrome P450, Porphyria related pages.



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